By Alan G. Rose
This atlas presents a finished representation and outline of a variety and variety of pathologic methods and illnesses affecting the entire significant organs of the physique. Emphasis is put on how the anatomic constitution of alternative organs may well make sure the development of involvement via illness approaches and the way such styles may well relief within the right analysis of the gross pathology. occasionally, a number of illustrations of ailment tactics are given to teach evolution of the affliction. Histologic illustrations of chosen gross lesions also are integrated the place correct. The atlas is illustrated with greater than 1,200 colour photomicrographs. Atlas of Gross Pathology is key for practising pathologists, yet may also offer a pretty good origin for surgeons, internists, and obstetricians/gynecologists.
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"It is a miracle that anyone guy must have saw, learn, and written down quite a bit in one lifetime. " — Kenneth Clark
Painter, sculptor, musician, scientist, architect, engineer, inventor . . . possibly no different determine so absolutely embodies the Western excellent of "Renaissance man" as Leonardo da Vinci. Leonardo used to be now not content material, in spite of the fact that, to grasp a creative method or list the mechanics of a tool; he used to be pushed via an insatiable interest to appreciate why. His writings, pursuits, and musings are uniformly characterised through an incisive, probing, wondering brain. It used to be with this piercing highbrow scrutiny and unique clinical thoroughness that Leonardo undertook the research of the human body.
This unheard of quantity reproduces greater than 1,200 of Leonardo's anatomical drawings on 215 basically published black-and-white plates. The drawings were prepared in chronological series to exhibit Leonardo's improvement and development as an anatomist. Leonardo's textual content, which accompanies the drawings — occasionally explanatory, occasionally autobiographical and anecdotal — has been translated into English via the prestigious clinical professors Drs. O'Malley and Saunders. of their attention-grabbing biographical creation, the authors assessment Leonardo's place within the old improvement of anatomy and anatomical representation. each one plate is followed by means of explanatory notes and an assessment of the person plate and a sign of its dating to the paintings as a whole.
While awesome for his or her striking good looks and precision, Leonardo's anatomical drawings have been additionally a long way previous to all modern paintings and scientifically the equivalent of something that seemed good into the 17th century. not like so much of his predecessors and contemporaries, Leonardo took not anything on belief and had religion basically in his personal observations and experiments. In anatomy, as in his different investigations, Leonardo's nice contrast is the actually clinical nature of his tools. Herein then are over 1,200 of Leonardo's anatomical illustrations equipped into 8 significant components of analysis: Osteological procedure, Myological approach, Comparative Anatomy, apprehensive process, respiration procedure, Alimentary procedure, Genito-Urinary process, and Embryology.
Artists, illustrators, physicians, scholars, academics, scientists, and appreciators of Leonardo's notable genius will locate in those 1,200 drawings the precise union of artwork and technology. conscientiously certain and actual of their facts, appealing and colourful of their method, they continue to be at the present time — approximately 5 centuries later — the best anatomical drawings ever made.
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Extra info for Atlas of Gross Pathology: With Histologic Correlation
Qxd 5/12/08 12:22 PM Page 31 A B 1-46. A. Infective endocarditis of a normal aortic valve with perforation of two valve cusps. B. Histologic appearance of aortic valve infective endocarditis with focal basophilia due to presence of pus cells within vegetation on the cusp. qxd 5/12/08 12:22 PM Page 32 1-47. Massive ring abscess of aortic valve in a patient with Q fever endocarditis due to Coxiella burnetii infection. Surgical correction, including aortic root replacement, would be the only way to cure this patient.
1-58. Severe prosthetic stenosis of this St. Jude Medical mechanical prosthesis has resulted from bilateral thrombus at the hinge mechanism area that has led both cusps to be fixed in the slightly open position. qxd 5/12/08 12:22 PM Page 39 1-59. Cloth wear in this Starr-Edwards ball valve mitral prosthesis has led to partial detachment of the cloth from the cage struts. Abundant thrombus had become attached to the free cloth, and the cloth wear became apparent only after the thrombus had been cleared from the cloth surface.
Endocardial scarring near left ventricular apex due to organization of endocardial thrombi. E. Histologic evidence of myocyte hypertrophy, namely squared off (box car) nuclei. qxd 5/12/08 A 12:23 PM Page 49 1-76. Hypertrophic cardiomyopathy. A. Noteworthy features include massive concentric hypertrophy of left ventricle, inward bulging interventricular septum with mirror image plaque of anterior mitral leaflet, and reactive thickening of anterior leaflet of mitral valve. Note that the mirror image plaque lies more inferiorly than the mitral valve because, during life, tension in its papillary muscles holds the valve at a lower level than after death.