Atlas of Gross Pathology: With Histologic Correlation by Alan G. Rose

By Alan G. Rose

This atlas presents a finished representation and outline of a variety and variety of pathologic methods and illnesses affecting the entire significant organs of the physique. Emphasis is put on how the anatomic constitution of alternative organs may well make sure the development of involvement via illness approaches and the way such styles may well relief within the right analysis of the gross pathology. occasionally, a number of illustrations of ailment tactics are given to teach evolution of the affliction. Histologic illustrations of chosen gross lesions also are integrated the place correct. The atlas is illustrated with greater than 1,200 colour photomicrographs. Atlas of Gross Pathology is key for practising pathologists, yet may also offer a pretty good origin for surgeons, internists, and obstetricians/gynecologists.

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Qxd 5/12/08 12:22 PM Page 31 A B 1-46. A. Infective endocarditis of a normal aortic valve with perforation of two valve cusps. B. Histologic appearance of aortic valve infective endocarditis with focal basophilia due to presence of pus cells within vegetation on the cusp. qxd 5/12/08 12:22 PM Page 32 1-47. Massive ring abscess of aortic valve in a patient with Q fever endocarditis due to Coxiella burnetii infection. Surgical correction, including aortic root replacement, would be the only way to cure this patient.

1-58. Severe prosthetic stenosis of this St. Jude Medical mechanical prosthesis has resulted from bilateral thrombus at the hinge mechanism area that has led both cusps to be fixed in the slightly open position. qxd 5/12/08 12:22 PM Page 39 1-59. Cloth wear in this Starr-Edwards ball valve mitral prosthesis has led to partial detachment of the cloth from the cage struts. Abundant thrombus had become attached to the free cloth, and the cloth wear became apparent only after the thrombus had been cleared from the cloth surface.

Endocardial scarring near left ventricular apex due to organization of endocardial thrombi. E. Histologic evidence of myocyte hypertrophy, namely squared off (box car) nuclei. qxd 5/12/08 A 12:23 PM Page 49 1-76. Hypertrophic cardiomyopathy. A. Noteworthy features include massive concentric hypertrophy of left ventricle, inward bulging interventricular septum with mirror image plaque of anterior mitral leaflet, and reactive thickening of anterior leaflet of mitral valve. Note that the mirror image plaque lies more inferiorly than the mitral valve because, during life, tension in its papillary muscles holds the valve at a lower level than after death.

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