An Introduction to Male Reproductive Medicine by Craig Niederberger

By Craig Niederberger

An creation to Male Reproductive medication is written particularly for readers looking access into this fast-moving, advanced area of expertise with a pretty good realizing of the topic. the 1st chapters hide the anatomy and body structure, medical evaluate, surgical procedure, medication, genetics and laboratory trying out eager about the present review and therapy of the infertile male, and the ultimate bankruptcy describes the interplay of the sector with lady reproductive drugs. in the course of the ebook, references are at once made to the fourth version of the key textual content within the strong point, Infertility within the Male, edited by way of Larry Lipshultz, Stuart Howards and Craig Niederberger, permitting readers to extend their knowing of particular components the place wanted. each one bankruptcy is written by means of a well-renowned professional in a simple to keep on with, casual type, making the textual content perfect for college students, citizens and basic physicians who're trying to raise their common wisdom of the sphere.

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Similarly, spermatozoa retrieved from the testis can fertilize oocytes in intracytoplasmic sperm injection cycles, but sperm motility and acrosome reaction are not essential for pregnancies to be achieved by that procedure. Sperm movement through the epididymis is positive and pendular, as the fluid moves back and forth in the tubule. This movement establishes a potential for sperm mixing, as the cells make their way down the epididymal tubule. The propelling forces for sperm transport through the epididymis are hydrostatic pressure from fluid secretion in the testis and peristaltic contractions of the tubule.

It is less clear what kinds of external application of heat, if any, lead to impaired sperm. A man crossing his legs, for example, raises his scrotal temperature by about 1 C. It is hard to imagine that men evolved so that the act of throwing one thigh over another quashed the chance of offspring. Similarly, laptops and tight underwear mildly increase scrotal temperature, but the actual reproductive effect of these elevations is not yet established. However, cooking the scrotum in the higher temperatures of Jacuzzi baths and saunas is more likely to lead to a temporary reduction in sperm production, and I typically counsel a man having a difficult time impregnating his wife to favor showers over hot baths during treatment.

The occurrence of acrosomal exocytosis facilitates sperm penetration through the zona pellucida, and exposure of certain molecules on the sperm equatorial segment that participate in fusion with the oolemma. During penetration, spermatozoa beat their tails vigorously. It has yet to be ascertained whether spermatozoa would complete zona pellucida penetration solely by physical thrust (mechanical hypothesis) or requiring enzymatic activity without the contribution of motility (enzymatic hypothesis), or finally with the contribution of both mechanisms.

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